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doi: 10.1111/dom.12937 51 RodbardHWLingvayIReedJde la RosaRRoseLSugimotoDet al

Preclinical data show this additive-to-synergistic interaction: each pathway potentiates the other's pituitary response, producing larger GH pulses without proportionally increasing side effects

Patient protection requires specific verification procedures and ongoing medical supervision, particularly when considering alternative medication sources

Side effects are primarily gastrointestinal, including diarrhea, constipation, and abdominal discomfort, ironically similar to GLP-1 medications but much milder