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Some practitioners implement cycling approaches (such as 12 weeks on, 4-8 weeks off), though no published research directly compares continuous versus cycled protocols
Comparing Different Measurement Units (mcg vs mg) Its important to know the difference between micrograms (mcg) and milligrams (mg) when talking about B12 doses
Supplement Success Rates High-dose oral supplements (1000-2000 micrograms daily) prove effective for many patients with mild to moderate deficiency
Initial signs of response typically appear by week 3-4, with meaningful results developing through weeks 5-8
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