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Tumour hypoxia in driving genomic instability and tumour evolution
In the controlled adult trial (Study 7), 6% (21/358) of VYVANSE-treated patients discontinued due to adverse reactions compared to 2% (1/62) of placebo-treated patients
The participant must be at least 18 years old and: Have a BMI of 35 or greater, or Have a BMI of 30 or greater with a diagnosis of diastolic heart failure, uncontrolled hypertension or chronic kidney disease Stage 3a or higher, or Have a BMI of 27 or greater with pre-diabetes, previous myocardial infarction or stroke, or symptomatic peripheral artery disease
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