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Immunohistochemistry was used to show that hydroxysteroid dehydrogenase-like 2 (HSDL2) expression levels in tissues was lower compared with those in matched neighboring non-tumor bile duct tissues

[13] Tyrosinase is directly inhibited through chelation of the copper site by the thiol group

Consequently, synthetic biology increasingly focuses on the development of multilayered biocontainment strategies that integrate metabolic dependencies, programmable genetic circuits, and multiple orthogonal triggers