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High concentrations of 4HNE have been associated with different processes such as apoptosis, cell differentiation, altered gene expression and with several diseases correlated to redox imbalance such as neurodegenerative and cardiovascular diseases, metabolic syndrome, and cancer 15

AOD 9604 10mg was easy to verify against the listed batch information

Replacement of Asp90 had a rather moderate but significant effect for PfGrx catalysis as expected