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Craig, T
Clinical trials show Zepbound reduces high-sensitivity C-reactive protein (hs-CRP) and may decrease inflammatory cytokines like TNF-, IL-6, and IL-1
This situation might be regulated by the overexpression of mitochondrial ATPase inhibitor 1 (ATPIF1) (34, 63)
A specific oxidoreductase, previously known as apoptosis-inducing-factor mitochondrial-2 (AIFM2), capable of recycling reduced ubiquinol (Co-enzymeQ 10 H 2 ) from ubiquinone at the expense of NAD(P)H, has been presented as a potential ferroptosis inhibitor due to the fact that its overexpression complements the loss of GPx4 in PFA1 and human fibrosarcoma (Figure 2)
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