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Interestingly, the authors show that IgG mediates macrophage infiltration in adipose tissue and that IgG can engage the insulin receptor via its CH3 domains, thereby reducing signaling in response to insulin

Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor- and bone morphogenetic protein

Sarma SM, Singh DP, Singh P, Khare P, Mangal P, Singh S, Bijalwan V, Kaur J, Mantri S, Boparai RK (2018) Finger millet arabinoxylan protects mice from high-fat diet induced lipid derangements, inflammation, endotoxemia and gut bacterial dysbiosis