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osmoprotectants such as soluble sugars and free proline
If you escalate from 5 mg to 7.5 mg tirzepatide at week 8, expect a 2-3 week window of renewed headache risk, but usually milder than the initial episode because your hydration habits have improved
Cortisol also raises the brain's reward sensitivity, so high-calorie foods feel more comforting, and this is part of why cortisol and sugar cravings tend to show up together
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