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Researchers observed that MC1R activation by MT-1 stimulates adenylyl cyclase, increasing intracellular cAMP, which activates CREB (cAMP response element binding protein) and induces MITF (microphthalmia-associated transcription factor) expression
In the C32E8.9 OE strain, GFP was detected throughout the body, while mCherry expression was restricted to the pharynx, confirming successful transgene expression
:( What, why?!
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