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GSH is exclusively degraded at the extracellular level by cells expressing -glutamyltranspeptidase (GGT), such as those of the hepatobiliary tree and of other organs like the heart, kidney, lungs, pancreas, and seminal vesicles

To view or add a comment, sign in JAMA Psychiatry Editor in Chief Dost ngr, MD, PhD, explains his 2025 pick for Editors Choice: Clinical Trials of the Year

(2025, September 30)

Allison Whitten Pfizer's LITFULO meets primary endpoints in Phase 3 vitiligo trials Pfizer reported topline results from two Phase 3 trials of LITFULO (ritlecitinib) in nonsegmental vitiligo, with both the 50 and 100 milligram once-daily doses meeting co-primary endpoints for facial and total body repigmentation over placebo at Week 52