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For broader disease context, the curated Diabetes Articles category summarizes how multiple pathways converge on glucose control
Comparators for third-line treatment consisted of canagliflozin 300 mg, empagliflozin 25 mg, dapagliflozin 10 mg, and sitagliptin 100 mg
Hence, because some of the cardiovascular benefits of SGLT2is are related to their hemodynamic effects, while those of GLP-1RAs are mainly related to their anti-atherogenic/anti-inflammatory actions, the two classes of medications may produce an additive cardiovascular benefit [11]
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