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injection of exenatide dampened cocaine-driven septal dopamine elevation, mediated by postsynaptic GLP-1R signaling that retrogradely regulates presynaptic dopamine transporter function [106]
A growing body of medical research and adverse events reported to the U.S
New therapies are expanding, populations are ageing and demand keeps rising
There are several Phase 3 trials evaluating GLP-1s for conditions, such as metabolic dysfunction-associated steatohepatitis (MASH), prediabetes, Alzheimer's disease, diabetic retinopathy and osteoarthritis of the knee (in patients with obesity)
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