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Glucagon is also involved in acutely regulating glucose homeostasis and administration of pharmacological doses of glucagon in animal models for diabetes or obesity has demonstrated regulatory effects on lipid metabolism, energy expenditure, and food intake ( The GLP-1/glucagon agonist cotadutide (MEDI0382) is the compound of this dual-receptor agonist class that is the most advanced in clinical development
2.4 Comment on psoriatic arthritis study While the majority of studies focus on PsO and its association with T2DM or MetS, there is only one small study specifically investigating PsA
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19 The search strategy was designed and conducted by a medical librarian (L.C.H.) with input from the studys principal investigator
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