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Although the mechanisms are not yet fully understood, rodent and human studies show that GIP plays a role in the regulation of lipolysis and lipogenesis in adipose tissue, which could contribute to improved lipid homeostasis and whole body energy metabolism [23, 24]
Further research is needed to better characterize these mechanisms in humans
The long-term efficacy and maintenance of weight loss with Semaglutide GLP-1 are still under investigation
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