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This complex process means that conditions affecting the stomach or intestines can significantly impair B12 absorption, including pernicious anaemia, atrophic gastritis, previous gastric surgery, coeliac disease, Crohn's disease, and long-term use of certain medications (such as metformin, proton pump inhibitors, and H2 antagonists)

Symptoms can include low muscle tone, weakness in their muscles, trouble exercising, breakdown of muscle tissue that can lead to a condition called rhabdomyolysis, and increased amounts of a molecule called creatine kinase

Huge changes dont need to be made to the commercial model. Ideallys researchers encourage marketers to pause, assess their current consumer base and identify optimization opportunities

PMID: 34676557 Solvent & Solubility In Vitro : H 2 O : 50 mg/mL ( 124.41 mM