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Considering the potential of secondary bile acids to increase L-cells and GLP-1 secretion by TGR5, TGR5 agonists are promising drug candidates for increasing L-cells and GLP-1 secretion [180, 181]
Notices have also been sent to defaulting entities," the government said, warning that "regulatory surveillance will continue to be intensified in the coming weeks, and non-compliances will be dealt strictly with actions, including cancellation of licenses, penalties, and prosecution under applicable laws. It is important to reiterate here that the drug has been approved in India with condition of prescription by endocrinologists and internal medicine specialists and for some indications by cardiologists only," the health and family welfare ministry said in a statement
Mice challenged with lipopolysaccharide/ Brucella abortus for 19 days exhibited an increase in immobility time, hyperalgesia, and serum TNF- levels