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Injection site reactions Redness, mild swelling, itching, or small nodules at the injection site occurred in 5 to 15% of trial participants
RNA sequencing and data analysis To investigate the molecular mechanisms driving TBI-induced secondary brain injury, transcriptomic profiling was conducted by next-generation sequencing on post-injury day 3 ( n = 3 per group), in accordance with a previously reported method (Yang et al., 2025)
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In this review, we summarize the existing data on these conditions and discuss the molecular mechanisms underlying the potential effects of KD, including anti-inflammatory and antioxidant pathways, modulation of signaling cascades, and interactions with the gut microbiota
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