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4.1 Limitations and implications for practice This meta-analysis has several limitations that should be considered when interpreting the findings

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For the preparation of 1 ml adjuvanted protein subunit vaccine, 25 g or 50 g of each rEE2 and rMCP antigen (50 g or 100 g total antigen) were mixed with Montanide Incomplete Seppic Adjuvant (ISA) 201 VG (SEPPIC, Paris, France) to produce a water-in-oil-in-water (W/O/W) vaccine emulsion