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Although long-term safety and efficacy require further evaluation, current evidence positions GLP-1 RAs as promising therapeutic agents in translational geroscience, with the potential to mitigate age-related physiological decline and promote a longer, healthier lifespan

Vitamin B12 deficiency results in reduced appetite and growth rates, ill thrift, infertility and reduced wool and milk production

Behavioral Anchors Cognitive behavioral therapy techniques such as pre-commitment (planning meals 48 hours ahead), stimulus control (removing high-calorie snacks from the home), and self-monitoring (daily weigh-ins) reduce weight regain velocity

Based on multi-omics approach, liver fluke-related cholangiocarcinoma cases are enriched in ERBB2 amplifications and TP53 mutations compared to those non-liver fluke-related cholangiocarcinoma cases (347)