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L-Carnitine is often available through oral or injectable forms
Furthermore, at the intestinal level, TCDCA-mediated activation of FXR leads to impaired nutrient-sensing mechanisms that regulate glucose homeostasis 273
Besides CNS-induced changes in the intestinal microbial environment, the neuroendocrine system can directly interact with microbiota via release of signaling molecules, like catecholamines, 5-HT, dynorphin, and cytokines, from neurons, immune cells, and ECCs (424, 425)
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