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Opening of the VGCCs evoked by membrane depolarisation, produced by increasing extracellular K + ([K + ] o ) to 70 mmol/l, stimulated glucagon secretion by over threefold, and this response was reduced by 60% by GLP-1(936) (Fig
PMID 8405712
That said, individual patients sometimes report mood changes, particularly anhedonia or flattened affect
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