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When under oxidative stress (OS) conditions, Hb is oxidized, it binds to the cytoplasmic domain of membrane protein band 3, triggering the formation of aggregates and the covalent linkage of natural anti-band 3 antibodies that may lead to premature RBC removal by splenic macrophages [1, 9]
Multiple forms of mouse glutathione S-transferases
Furthermore, KPV enters intestinal epithelial cells through the PepT1 oligopeptide transporter, achieving intracellular concentrations that receptor-restricted peptides cannot reach
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