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Retrieved 9 February 2017
SPIOMET and Multi-Drug Approaches A newer treatment strategy, SPIOMET , combines low-dose spironolactone (50 mg/day) , pioglitazone (7.5 mg/day) , and metformin (850 mg/day)
Some researchers prefer this option during the initial low-dose escalation phase, then switch to a higher concentration for maintenance dosing
Furthermore, correcting a choline deficiency restores normal liver function, but that is a nutrient-correction benefit, not a pharmacological weight loss effect
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