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One 2016 study published in Pharmaceutical Research found that supplementing with NAC inhibited fat mass and obesity development in mice that were fed a high-fat diet
NRF2 redirects glutamate to glutathione synthesis and cystine uptake and away from TCA cycle anaplerosis, therefore limiting glutamate as a carbon source for TCA cycle and mitochondrial activity (Sayin et al
Data availability Anonymized data will be shared by request from any qualified investigator
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