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Current safety data for 5-amino-1MQ appears favorable for short-term use (8-12 week cycles), with no significant toxicity observed in preclinical studies at therapeutic doses
Selectivity The methylquinolinium inhibitors proved selective for NNMT, sparing structurally related methyltransferases and the NAD+ salvage-pathway enzymes, which makes 5-Amino-1MQ a clean research tool [1]
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