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It is a molecule naturally produced by the human body, and decades of clinical use across both topical and injectable applications have not identified significant adverse effects

Because injections skip this step, the absorption rate of B12 is significantly higher and more predictable than oral supplements

To date, the ability of NMDA receptor antagonists (eg, PCP, ketamine) to reproduce important aspects of the illness, including negative symptoms and cognitive deficits, remains one of the strongest clues to underlying etiology

Vitamin B12 is a water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function