The proposed mechanism involves preventing GABA receptor downregulation, counteracting compensatory NMDA receptor sensitization, and stabilizing benzodiazepine receptor configuration
Biguanide MC001, a dual inhibitor of OXPHOS and glycolysis, shows enhanced antitumor activity without increasing lactate production
Foods Rich in Glutathione Precursors Since cysteine availability is the rate-limiting factor for glutathione synthesis, foods rich in cysteine and sulfur-containing amino acids are particularly important [2][9]: High-cysteine protein sources: Whey protein, eggs, chicken, turkey, pork, beef, fish Sulfur-rich vegetables (also activate Nrf2): Broccoli, Brussels sprouts, cauliflower, kale, cabbage, garlic, onions, shallots Glycine-rich foods (collagen sources): Bone broth, gelatin, skin-on chicken, pork rinds Glutamic acid sources: Tomatoes, mushrooms, parmesan cheese, soy sauce, fermented foods Practical Notes Cooking reduces glutathione: Raw fruits and vegetables contain more glutathione than cooked versions
A randomized clinical pilot study involving children with acute lymphoblastic leukemia (ALL) found that milk thistle was associated with a reduction in liver toxicity caused by chemotherapy
