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PTMetaD-WTE, parallel tempering metadynamics in a well-tempered ensemble
days 1 to 30): 1.5 mg orally once a day Dose escalation (days 31 to 60): 4 mg orally once a day Maintenance dose (day 61 and onward): If no additional glycemic control is needed: Maintain at 4 mg orally once a day
International Journal of Clinical Practice, 74 (6), e13493
It is a poorer fit, or warrants caution, in patients with known sulfur or sulfite sensitivity, in poorly controlled asthma, and in anyone whose expectations are anchored to unproven claims particularly cosmetic skin-lightening
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