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GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a tripeptide naturally present in human blood plasma at concentrations averaging 200 ng/mL at age 20, declining to approximately 80 ng/mL by age 60

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Storage duration critically impacts effectiveness - reconstituted GHK-Cu lasts only 21-28 days refrigerated due to copper oxidation concerns (shorter than most peptides), requiring strategic reconstitution of amounts usable within this window rather than preparing entire vials at once