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13 MELANOSIS Diagnosis Dark (usually black) flat, smooth, 5- to 25-mm patch Asymmetric or angular configuration Located primarily on nonkeratinizing (mucosal) tissue Unchanging appearance (if patient has previously been aware of the lesion) Incisional biopsy to rule out dysplasia and malignancy Dermoscopy of lentiginosis requires an experienced dermoscopist, and there is no one pattern

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