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These secondary messengers are hypothesized to increase calcium release from intracellular stores and activate protein kinase C (PKC), together contributing to vesicular secretion from somatotroph cells
This systematic review and meta-analysis aimed to evaluate and compare the effectiveness of sublingual and oral vitamin B12 administration in comparison with intramuscular (IM) injections, both for improving serum cobalamin and reducing homocysteine levels
IN DFO in rats resulted in drug concentration in the cortex approximately 10-fold higher than an equivalent intravenous dose, with lower systemic concentrations and systemic side effects (Hanson et al., 2009)
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