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Contacts and hydrogen bond persistency are quantified as the percentage of frames (over all the frames obtained by merging the different replicas) in which protein residues formed contacts or hydrogen bonds with the ligand
On March 1, Hani Soudah, MD, PhD, Associate Professor of Medicine in the Division of Endocrinology, Metabolism, & Lipid Research at WashU Medicine, along with collaborators, published a new systematic review and meta-analysis examining the broader physiological effects of semaglutide titled A Systematic Review and Meta-Analysis of Semaglutide Effects on Adipose Tissue and Emerging Effects on Brain and Cognition . Semaglutide, widely used to treat obesity and type 2 diabetes, has recently drawn attention for its potential influence beyond metabolic health
Hassouna R, Fernandez G, Lebrun N, Fiquet O, Roelfsema F, Labarthe A, et al
The multiple-target drug had better effects, while the single-target drugs showed a significant improvement in steatosis and glucose metabolism, particularly with GLP-1RAs
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