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Given the ease in accessing blood samples, blood-based biomarkers are frequently used as measures of REDOX state (e.g., refs
In viral hepatitis, HBV/HCV trigger ER stress and upregulate NOX1/NOX4, increasing ROS
10.1146/annurev.pa.25.040185.003435 Ann Rev Pharmacol Toxicol
This has resulted in development of the clinically active antiepileptic drug tiagabine which is a specific inhibitor of GAT1 (34) and more recently such studies have been focusing on development of inhibitors acting preferentially on non-GAT1 transporters (69)
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