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The effects of NTZ were compared to those of the standard antioxidant, N-acetyl cysteine (NAC), as a well-documented hepatoprotective agent known to inhibit ER stress, and to those of 4-phenyl butyrate (4-PBA), a standard ER stress inhibitor (Soliman et al., 2019)

Often referred to as the body's "master antioxidant," glutathione plays a crucial role by protecting cells, supporting detoxification and maintaining immune function

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Major birth abnormalities of the ears, eyes, face, skull, and brain may result with even a single dosage of isotretinoin during pregnancy