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Heres how each one helps: Glutathione reduces melanin production and brightens overall skin tone Tranexamic acid stops inflammation that causes dark spots and melasma (brown patches) Niacinamide improves skin texture, reduces redness, and strengthens the skin barrier Together, these three ingredients attack dark spots from different angles, giving you faster and better results

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74, 75, 76, 77 The underlying mechanism of increased eNOS expression likely involves increased endothelial production of hydrogen peroxide, which has been shown to increase the expression of eNOS at the transcriptional and translational level