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Their ability to target both direct (TGF- inhibition) and indirect (metabolic, inflammatory) drivers of fibrosis may provide a powerful, synergistic therapeutic approach
Since a 10mg/ml vial contains 100 doses at the lowest dose (.10 mg) and 25 at the next lowest dose (.25 mg), it has far more of the drug than you could use in a month (1 dose a week)
In GPX4 knockout mice, the incidence and mortality in spontaneous AKI increased significantly 76
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