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Phase 1 showed the drug was real
Tirzepatide produced a mean weight reduction of 20.2% compared to 13.7% with semaglutide a statistically significant 6.5 percentage point difference
The rates are broadly similar
doi: 10.1210/clinem/dgaa863 Summary Keywords obesity, insulin-resistance, Tirzepatide, pathophysiology, GIP, GLP - 1, clinical trials, arterial hypertension Citation Corrao S, Pollicino C, Maggio D, Torres A and Argano C (2024) Tirzepatide against obesity and insulin-resistance: pathophysiological aspects and clinical evidence
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