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The article separately notes that these agents may alter gallbladder function, which is part of why that history is called out on its own line
But that hasn't thwarted use in many cases
3 Mechanism of AS-IV in arrhythmia The underlying pathological mechanisms of arrhythmia include ischemia-reperfusion injury, fibrosis, and ion channel dysfunction, all of which disrupt the normal electrical conduction and automaticity of the heart
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