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conducted in vivo experiments that showed a significant increase in TPH2 mRNA in the prefrontal cortex of rats treated with chronic 1,25(OH)2D administration [2]
When overexpressed, MAO causes an excess of ROS in cells that injures mitochondria.[ref] Related article: MAO-A and MAO-B: Neurotransmitter levels, genetics, and studies SOD2 encodes an enzyme that converts ROS (reactive oxygen species) in the mitochondria
According to this study, probiotics alone did not significantly reduce depressive symptoms as much as synbiotics did
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