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98 Although located in the sinoatrial node, GLP-1 RAs influence the cardiovascular system through several other mechanisms, including the use of myocardial glucose, improvement of left ventricular function, myocardial ischaemic protection, increased heart rate, vasodilation, anti-atherosclerotic effects, and blood pressure reduction

[2] Insulin-like Growth Factor Binding Proteins (IGFBPs) are a category of proteins that may regulate the availability of Insulin-like Growth Factors (IGFs) within the bloodstream, possibly influencing their interactions with various tissues

This personalized approach ensures that any adjunctive therapy complements your GLP-1/GIP treatment rather than adding complexity without clear benefit

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