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Moreover, Gln is an essential substrate for the immune system, and prolonged use of Gln metabolic inhibitors might weaken the anti-tumor immune response ( 2 The role of Gln metabolism in tumor Emerging evidence shows that Gln metabolism is involved in tumor progression in two specific ways ( Figure 1 )

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Their main disadvantages, however, are their high cost, long lifespan, and the need for specialized large-animal facilities

Glutathione is a natural protein molecule that is naturally found in a majority of lifeforms from plants, animals to bacteria and even little mushrooms