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Expect a transient GI adjustment period
12,13 Modifications to prolong the half-life of GLP-1 RAs include sequence substitutions conferring resistance to DPP-4, along with acylation (liraglutide and semaglutide), covalent bonding to modified Ig fragment crystallisable domain (dulaglutide), or covalent bonding to albumin
Importantly, participant age was not associated with BBB permeability in our cohort with long COVID, suggesting that BBB disruption is more probably due to the neurological symptoms of long COVID
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