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Misconception: you need special thyroid tests before starting tirzepatide No special thyroid tests are required beyond standard medical assessment

i , Immunoblot analysis of SYVN1 from SLC33A1 -knockout HEK293T cells complemented with a vector control or SLC33A1 cDNA expressing sgRNA targeting intergenic region or two different sgRNAs targeting SYVN1

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However, if you are high risk for heart disease, have had a heart event or the equivalent (stroke, stent), or do not require 15-20% weight loss, semaglutide / Wegovy may be a better choice