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These peptides work through entirely different biological pathways, and understanding those differences is the key to optimizing your protocol

This work was supported by the National Key Research and Development Program of China (2023YFC2306002), the National Natural Science Foundation of China (82372227 and 82172245), the Beijing Natural Science Foundation (L256024, 7264275), the High-level Talents Program of the Beijing Health System, and Funding for Reform and Development of Beijing Municipal Health Commission (EYGF-BD-03)

To further test whether the incorporation of a targeting motif could enhance the binding of chimeric peptides in vivo , we used smearing FITC-peptides at the mouse back for 24 h and tracked the peptide location of the skin slices by fluorescent microscopy

In those investigations DSIP was generally well tolerated, and severe toxicity was not consistently reported