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Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm - 2020 Executive Summary

Nasal spray considerations: Typically lower bioavailability than injection, requiring somewhat higher doses Faster onset in some users due to direct CNS access More convenient and less intimidating for needle-averse individuals Requires properly calibrated spray bottles for accurate dosing Converting from injectable to nasal dosing is not straightforward

Use natural, cold-pressed oils like coconut or olive oil, since heat oxidizes fats in refined oils, and be sure to limit intake of antibiotic- and hormone-laden foods, such as farm-raised meat or fish

Claim scrubbing through a GI-optimized clearinghouse catches modifier 59 edit pair conflicts before the claim reaches the payer