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this phenomenon has been linked with the increased resistance at doxorubicin treatment due to the lack of CT2 in the cell membrane that, in turn, impairs drug entry into cancer cells (Novak et al., 2015)
Director, Diabetes Care Clinic, VA Medical Center San Diego Dr
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J Biol Chem 256:1238712392 Larraufie M-H, Yang WS, Jiang E et al (2015) Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility
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