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It protects cartilage from further damage
Reverse Transcription Quantitative Polymerase Chain Reaction (RT-qPCR) and Western Blot (WB) are used to detect the expression of characteristic and inflammatory genes, and immunofluorescence staining is used to investigate the expression of fibrosis marker proteins in cells
First, G6PD-d limits the production of important substrates for biosynthesis, cell growth and proliferation
Moreover, various pathological changes can emerge together, in sequence or in isolation being disease-, stage-, and context-specific, and are influenced by age and systemic pathologies
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