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Selenium supplements contain sodium selenite or selenomethionine, and the main difference between them is that, after saturation of selenoproteins, selenite is excreted whereas selenomethionine can further increase serum selenium through its incorporation into proteins (1, 4)

Cysteine residues were searched with a static modification for carboxyamidomethylation (+57.02146 Da), and N-termini and lysine residues were searched with a static modification corresponding to the TMT tag (+229.1629 Da)

Lys105 has a dual function for the oxidative and reductive half-reaction of ScGrx7 resulting in a decrease of all k cat app , k cat app / K m app and 1/ values for K105A/Y/E (Fig