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In a study, the silico analysis of gene expression data and analysis of serum vitamin B6 metabolites in patients with psoriasis indicated altered vitamin B6 metabolism both locally and systemically

If you let it go for too long, it can cause problems in your nervous system such as: Vision problems Memory loss A pricking or numbing sensation Difficulty speaking or walking due to ataxia (loss of physical coordination) Damage to your extremities (hands, feet, arms, etc.), particularly your legs Other problems could include Infertility (this should go away with B12 treatment) Stomach cancer Bleeding and infections Damage your heart, brain, bones, and other organs in your body If you're pregnant and don't get enough vitamin B12, your baby is at risk of a serious birth defect called a neural tube defect

Eur J Pharmacol 570:212221 Veljaca, M, Krnic, Z and Brajsa, K (2002) The development of PL 14736 for treatment of inflammatory bowel disease

Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial