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Unlike other drugs such as Mounjaro and Zepbound, which activate both GLP-1 and GIP receptors, MariTide works as a GLP-1 receptor agonist and a GIP receptor antagonist
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Only statistically significant results are presented in the main text, while non-significant findings are reported in Supplementary information
Withdrawal symptoms can include Increased appetite Decreased satiety Elevated blood sugar levels Weight gain Elevated blood pressure and other cardiovascular changes A study from a 2022 clinical trial that tested semaglutide treatment for weight loss found that participants had regained about two-thirds of their initial weight loss on average, and many patients also experienced raised blood pressure levels
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